Carbamazepine Acute Toxicity

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Possible carbamazepine toxicity with terbinafine.

OBJECTIVE To report a case of carbamazepine and terbinafine interaction resulting in an elevated level of carbamazepine and associated symptoms of toxicity. CASE SUMMARY A 50-year-old Caucasian man developed an elevated carbamazapine level after starting terbinafine, which caused symptoms of toxicity with gait ataxia, dizziness and falls. DISCUSSION This is a first report of a drug-drug int...

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Dystonia associated with carbamazepine toxicity.

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Acetaminophen is a widely used analgesic that can cause acute liver failure when consumed above a maximum daily dose. Certain patients may be at increased risk of hepatocellular damage even at conventional therapeutic doses. We report a case of a 34-year-old man on carbamazepine for complex partial seizures who developed acute liver and renal failure on less than 2.5 grams a day of acetaminophe...

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the effect of lithium on acute toxicity of carbamazepine in mice

the effects of chronic administration of lithium, on acute toxicity of carbamazepine (cbz) in mate albino mice was studied and the ld50 values were determined from dose-probit curves. the results showed that in lithium pretreated animals (animals consumed drinking water contraining 600 mg/l lithium carbonate for 10 days) the ld50 value (the doese corresponding to probit 5) of cbz decreased sign...

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Acute interstitial pneumonitis induced by carbamazepine.

A 62 year old man treated with carbamazepine for 3 months developed eczema and acute interstitial pneumonitis. A lymphocyte-stimulation test was reactive to carbamazepine. Withdrawal of the drug resulted in prompt improvement. Only 10 cases of this type of drug-induced lung disease have previously been reported.

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ژورنال

عنوان ژورنال: Pediatric Neurology Briefs

سال: 1992

ISSN: 2166-6482,1043-3155

DOI: 10.15844/pedneurbriefs-6-9-9